Loud noise can cause permanent hearing loss. Noise-induced hearing loss is painless and usually happens over time. Hearing an extremely loud sound, like . The most common causes of hearing loss are: Aging Noise exposure Head trauma Virus or disease Genetics Ototoxicity. acquired, genetic and unknown. There are many causes for hearing loss: 1. Acquired HL: infectious and pharmaceutical agents known as teratogens would affect the sense of hearing. HL could occur by phys iological, biochemical or infectious factors. However, genetic background has an important effect on its occurrence. The risk.